Relationship between Biomarkers of Carbohydrate, Energy and Adipokine Metabolism in Patients with Acute Myocardial Infarction and Type 2 Diabetes Mellitus

The purpose of the study was to examine indicators carbohydrate, energy and adipokine metabolism in acute myocardial infarction patients with or without type 2 diabetes mellitus. Materials methods. A total 134 ST-segment elevation presence absence mellitus aged 58.97 ± 7.92 years were examined Government Institution “L. T. Malaya Therapy National Institute Academy Medical Sciences Ukraine” Kharkiv Railway Clinical Hospital No. 1 “Center Healthcare” branch Public Joint Stock Company “Ukrainian Railway”. main group (group 1) included 74 comparison 2) represented by 60 control composed 20 otherwise healthy individuals. Serum concentrations insulin, adropin, irisin, fatty acid binding protein 4 C1q/TNF-related measured enzyme-linked immunosorbent assays. Results discussion. It found that levels glucose, HOMA-IR index increased when compared (p˂0.05). In mellitus, serum irisin significantly lower, while higher as those (p<0.05). Acute demonstrated lower adropin Negative correlations between blood glucose (r = -0.499, p<0.001), -0.495, -0.518, -0.304, p<0.02), -0.429, p 0.001), well positive 0.435, 0.001) revealed patients. negative -0.504, -0.520, 0.03), -0.546, p<0.001); insulin -0.361, 0.017), -0.396, 0.01), 0.018); -0.508, -0.436, 0.003), correlation 0.508, 0.007); 0.501, 0.001); 0.516, p<0.001). Conclusion. Characteristics are evidence violated both diabetic non-diabetic infarction. Relationships could indicate involvement these markers carbohydrate